By William W. Cohen
This ebook is designed particularly as a consultant for machine Scientists desiring an advent to cellphone Biology. The textual content explores 3 assorted aspects of biology: organic structures, experimental tools, and language and nomenclature. the writer discusses what biologists try to figure out from their experiments, how quite a few experimental systems are used and the way they relate to authorised suggestions in laptop technological know-how, and the vocabulary essential to learn and comprehend present literature in biology. The ebook is a useful reference device and a very good place to begin for a extra accomplished exam of cellphone biology.
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Additional resources for A Computer Scientist's Guide to Cell Biology
An example of an SDS-PAGE gel. Lanes 1-3 are a complex mixture of several substances, and lanes 4-6 show the corresponding mixture components after purification (via Western blotting, described below). The leftmost column is provided by the authors, and shows the molecular weights of substances that migrate to each level. Here the authors are demonstrating the effectiveness of the purification method used. From Mass spectrometric analysis of electrophoretically separated allergens and proteases in grass pollen diffusates, by Mark J Raftery , Rohit G Saldanha , Carolyn L Geczy and Rakesh K Kumar, Respiratory Research 2003, 4:10 Figure 27.
Gold. Both of these procedures (to put it moderately) tend to cause damage, so preserving a specimen in something like its native state is often a major challenge for electron microscopy. Work on using electron microscopes in close-to-normal conditions is an active area of research, however. William W. Cohen E 43 F Electron microscope images. (A) human HeLa cells (B) the inset in (A), further magnified. (C) hamster CHO cells, with some mitochondria shown in the inset. (D) actin filiments. (E) part of the intestinal cell of a 4-day old rat.
From “Activation, internalization, and recycling of the serotonin 2A receptor by dopamine”, by Samarjit Bhattacharyya, Ishier Raote, Aditi Bhattacharya, Ricardo Miledi, and Mitradas M. Panicker, PNAS, 2006;volume 103; pp. 15248-15253. Figure 24. Fluorescent microscope images. 42 A Computer Scientist’s Guide to Cell Biology One important type of microscope for use with fluorescent dyes is the confocal microscope, in which aggressive filtering is used, so that not only is reflected light filtered out, but also only light emitted by a very small part of the image is detected.
A Computer Scientist's Guide to Cell Biology by William W. Cohen