By Andrej Čretnik (ed.)
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Additional resources for Achilles Tendon
Collins, M. (2009). Variants within the COL5A1 gene are associated with Achilles tendinopathy in two populations. British Journal of Sports Medicine, 43(5), 357–365. September AV, Mokone, G. , Schwellnus, M. , & Collins, M. (2006). Genetic risk factors for Achilles tendon injuries. International SportMed Journal, 7(3), 201–215. , Schwellnus, M. , Noakes, T. , & Collins, M. (2008). The COL12A1 and COL14A1 genes and Achilles tendon injuries. International journal of sports medicine, 29(3), 257–263.
However, the functional promoter variant rs1800469 of the TGF-β gene was not found to cosegregate with Achilles tendon pathology in both South African and Australian Caucasian cohorts (Posthumus et al, 2010). The same investigators then examined the possible role of another variant (rs143383) within a second member of the TGF-β family, namely the growth differentiation factor 5 (GDF-5) gene, for association with Achilles tendon injury. They found that carriage of the TT genotype at the rs143383 locus was associated with Achilles tendon pathology in Australian cases and when the data were combined for both cohorts of Australian and South Africans (Posthumus et al, 2010).
2000). Thrombospondin 2, a matricellular protein with diverse functions. Matrix biology : journal of the International Society for Matrix Biology, 19(7), 557–568. , Schwellnus, M. , & Collins, M. (2011a). Range of motion measurements diverge with increasing age for COL5A1 genotypes. Scandinavian Journal of Medicine & Science in Sports. , Schwellnus, M. , & Collins, M. (2011b). The COL5A1 gene, ultra-marathon running performance and range of motion. An original investigation. International Journal of Sports Physiology and Performance.
Achilles Tendon by Andrej Čretnik (ed.)