Download PDF by Wilson Golder N.: AHFS Drug Information 2004

By Wilson Golder N.

ISBN-10: 0071375783

ISBN-13: 9780071375788

Offers scientific scholars 500 questions, solutions, and reasons to arrange for the biochemistry and genetics sections of the USMLE Step 1. the hot variation comprises many new questions within the two-step medical layout to simulate the USMLE Step 1.

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Sack, pp 3–29. ) Polymorphic loci have multiple alleles because of DNA sequence variation, including one or more with frequencies greater than 1%. This higher frequency and benign connotation differentiate polymorphic loci from those that harbor multiple disease-causing alleles. The DNA sequence changes may alter restriction sites [producing restriction fragment length polymorphisms (RFLPs)], change the numbers of repeated segments [producing variable numbers of tandem repeats (VNTRs)], or alter the genetic code (producing variant proteins, or protein polymorphisms).

Reverse transcriptase is an RNA-directed DNA polymerase. The RNA of retroviruses utilizes reverse transcriptase to synthesize DNA provirus, which in turn synthesizes new viral RNA. AZT inhibits DNA provirus production, but does not directly inhibit synthesis of new viral RNA. 26. The answer is e. (Murray, pp 412–434. Scriver, pp 3–45. Sack, pp 3–29. ) Reverse transcriptase is an RNA-dependent DNA polymerase that can synthesize first a single strand and then a doublestranded DNA from a single-strand RNA template.

E. qxd 11/14/01 10:37 AM Page 45 Gene Expression 45 63. Erythromycin is the antibiotic of choice when treating respiratory tract infections in legionnaire’s disease, whooping cough, and Mycoplasma-based pneumonia because of its ability to inhibit protein synthesis in certain bacteria by a. b. c. d. e. Inhibiting translocation by binding to 50S ribosomal subunits Acting as an analogue of mRNA Causing premature chain termination Inhibiting initiation Mimicking mRNA binding 64. An immigrant family from rural Mexico brings their 3-month-old child to the emergency room because of whistling inspiration (stridor) and high fever.

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AHFS Drug Information 2004 by Wilson Golder N.

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