By Sandra I. Kim MD PhD, Todd A. Swanson M.D. Ph. D
Those quickly and handy flash playing cards will tremendously help scholars in reviewing and studying the real information about pharmacology. all the 269 playing cards deals a short query and resolution, utilizing a set off word to assist scholars memorize and remember right responses. BRS Pharmacology Flash playing cards is a part of a chain of transportable flash playing cards overlaying microbiology, pathology, and now pharmacology. Designed to accompany BRS Pharmacology , those overview playing cards also will support scholars enrolled in different easy technological know-how or pharmacology classes or these getting ready for USMLE Step 1
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Additional resources for Brs Pharmacology (Board Review)
Rapid effect. Special Features: No longer used very much. Special Features: 5-10 mg/8 hr (or higher). : Trapped by thyroid. β particles cause highly localized tissue destruction. X-rays are diagnostically useful. I131 generally used due to short t_ (8 d). Absorption: 90% ends up in thyroid or urine. 10% absorbed by the rest of the organ systems. : Excretion, t_: Urine. 8 d. , eventually 50%). May require multiple exposures—up to a year (thioamides usu. used to cover hyperthyroidism in the interim).
Large ↓ in TG. Moderate ↓ in cholesterol & VLDL. Mild ↓ in LDL. Zeromoderate ↑ in HDL. s: Cutaneous flushing (92%), itching (49%), rashes (20%). Reduce w/aspirin pretreatment, admin. after meals, small init. dose gradually increased in size. Pruritis, dry skin, ↑ pigmentation, hepatotoxicity, n/v, dyspepsia, peptic ulceration, ↑ urinary frequency, dysuria, gout. High doses → hepatic/pancreatic dysfxn. Coadmin. anti-hypertensives → dizziness, syncope. Sustained-release preparations more commonly assoc.
S reduced if taken immediately prior to meals. _ dose + Metamucil™ → ↓ constipation & bloating, but sim. efficacy. : Binds bile acids in intestine → ↑ defecation of bile acids, ↑ conversion of cholesterol to bile acids, ↓ pool of hepatic cholesterol, ↑ activity of apoB/E receptor, ↑ LDL clearance, ↓ plasma cholesterol. Moderate ↓ in cholesterol & LDL. Mild ↑ in HDL. Zero-moderate ↑ in TG & VLDL. Absorption: Oral. No absorption. s: Flatulence, constipation, gas, n/v, steatorrhea. Supersaturation of cholesterol in bile → gallstones, need for cholecystectomy.
Brs Pharmacology (Board Review) by Sandra I. Kim MD PhD, Todd A. Swanson M.D. Ph. D